Abstract
Aim: This research aimed to estimate the potential impact of CaO nanoparticles at different concentrations on the
remineralization of enamel undergoing cariogenic attack.
Materials and methods: Eighteen enamel samples were prepared from sound molars to measure its calcium (Ca) and
phosphorus (P) contents by scanning electron microscope equipped with energy dispersive X-ray spectroscopy (SEM-EDS)
before and after exposure to cariogenic attack and treatment with saturated gum of 100% CaO nanoparticles (Group 1),
50% CaO nanoparticles (Group 2), and ƒ‹ϔ‹…‹ƒŽ saliva (Group 3). The research data were statistically analysed using the
one-way ANOVA and Bonferroni tests.
Results and discussion: Group 1 of treatment with 100% CaO nanoparticles demonstrated the largest content of Ca (77.8 wt
% ± 9.6) followed by Group 2 and 3 (66.6 wt% ± 1.5, 64.4 wt% ± 1.9, respectively). Conversely, Group 1 had the lowest
amount of P (18.9 wt% ± 3.9) followed by Group 3 and 2 (29.9 wt% ± 1.4, 31.0 wt% ± 1.1, respectively). The
demineralization is a reversible process which starts with Ca loss before P loss, so it is logical to use a recalcifying agent (Ca
containing agent) to enhance the ‡…ƒŽ…‹ϔ‹…ƒ‹on and regrowth of hydroxyapatite (HA) crystals where the P could be driven
from the saliva. CaO is rich with bioavailable Ca contents, favouring the remineralization of caries lesions. Furthermore, as
the CaO applied in a nano-size particle, it has the ability to diffuse actively through the tiny spaces of the etched enamel.
Conclusion: The use of saturated gum with CaO nanoparticles could overcome the cariogenic challenge. The Ca uptake
increased with the increased concentration of applied CaO nanoparticles.
remineralization of enamel undergoing cariogenic attack.
Materials and methods: Eighteen enamel samples were prepared from sound molars to measure its calcium (Ca) and
phosphorus (P) contents by scanning electron microscope equipped with energy dispersive X-ray spectroscopy (SEM-EDS)
before and after exposure to cariogenic attack and treatment with saturated gum of 100% CaO nanoparticles (Group 1),
50% CaO nanoparticles (Group 2), and ƒ‹ϔ‹…‹ƒŽ saliva (Group 3). The research data were statistically analysed using the
one-way ANOVA and Bonferroni tests.
Results and discussion: Group 1 of treatment with 100% CaO nanoparticles demonstrated the largest content of Ca (77.8 wt
% ± 9.6) followed by Group 2 and 3 (66.6 wt% ± 1.5, 64.4 wt% ± 1.9, respectively). Conversely, Group 1 had the lowest
amount of P (18.9 wt% ± 3.9) followed by Group 3 and 2 (29.9 wt% ± 1.4, 31.0 wt% ± 1.1, respectively). The
demineralization is a reversible process which starts with Ca loss before P loss, so it is logical to use a recalcifying agent (Ca
containing agent) to enhance the ‡…ƒŽ…‹ϔ‹…ƒ‹on and regrowth of hydroxyapatite (HA) crystals where the P could be driven
from the saliva. CaO is rich with bioavailable Ca contents, favouring the remineralization of caries lesions. Furthermore, as
the CaO applied in a nano-size particle, it has the ability to diffuse actively through the tiny spaces of the etched enamel.
Conclusion: The use of saturated gum with CaO nanoparticles could overcome the cariogenic challenge. The Ca uptake
increased with the increased concentration of applied CaO nanoparticles.
| Original language | English |
|---|---|
| Pages (from-to) | 20-26 |
| Number of pages | 7 |
| Journal | Journal of Research in Medical and Dental Science |
| Volume | 8 |
| Issue number | 2 |
| Publication status | Published - 2 Mar 2020 |
Keywords
- CaO nanoparticles, Demineralization, Remineralization