Use of Small-Molecule Crystal Structures To Address Solubility in a Novel Series of G Protein Coupled Receptor 119 Agonists: Optimization of a Lead and in Vivo Evaluation

James S. Scott, Alan M. Birch, Katy J. Brocklehurst, Anders Broo, Hayley S. Brown, Roger J. Butlin, David S. Clarke, Ojvind Davidsson, Anne Ertan, Kristin Goldberg, Sam D. Groombridge, Julian A. Hudson, David Laber, Andrew G. Leach, Philip A. MacFaul, Darren McKerrecher, Adrian Pickup, Paul Schofield, Per H. Svensson, Pernilla SoermeJoanne Teague

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Pharmacology, Toxicology and Pharmaceutical Science

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