Using automated extraction of hepatitis B tests for surveillance: Evidence of decreasing incidence of acute hepatitis B in England

L. J. Brant, M. Hurrelle, S. Collins, P. E. Klapper, M. E. Ramsay

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Surveillance of acute hepatitis B in England is necessary to estimate incidence, determine routes of transmission and inform public health actions. Here we describe an automated process to extract information on testing for markers of hepatitis B infection in English sentinel laboratories between 2002 and 2008. The resulting data were used to identify individuals with acute infections, describe their characteristics and estimate the incidence of infection. Two-thirds of acute infections were in males. Heterosexual exposure and injecting drug use were the main risks reported. Annual incidence was estimated at 1·3/100 000 person-years overall (1·7 and 0·6 for males and females, respectively) and declined each year. Automated extraction of hepatitis B markers, including quantitative results where available, can help to classify HBV status more accurately for surveillance. HBV incidence in England is at its lowest level in recent years. © 2011 Cambridge University Press.
    Original languageEnglish
    Pages (from-to)1075-1086
    Number of pages11
    JournalEpidemiology and infection
    Volume140
    Issue number6
    DOIs
    Publication statusPublished - Jun 2012

    Keywords

    • England
    • epidemiology
    • hepatitis B
    • incidence
    • surveillance

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