UV-C radiation induces apoptotic-like changes in Arabidopsis thaliana

Antoine Danon, Patrick Gallois

    Research output: Contribution to journalArticlepeer-review


    With a view to studying programmed cell death in plants at the molecular level, we report here for the first time that apoptotic-like changes are induced by UV radiation in plant nuclei. In Arabidopsis thaliana seedlings a UV-C dose of 10-50 kJ/m2 induces an oligonucleosomal DNA fragmentation which is reminiscent of the apoptotic DNA ladder described in animal cells. This DNA fragmentation was also detected in situ in protoplast nuclei as soon as 2 h after UV-C treatment. Moreover, UV-C induced a nuclear morphology characteristic of animal apoptotic nuclei. We propose that UV-C induction constitutes a powerful tool to compare the cellular response to irreversible UV damage in plants to that in animals and to study programmed cell death in A. thaliana. Copyright (C) 1998 Federation of European Biochemical Societies.
    Original languageEnglish
    Pages (from-to)131-136
    Number of pages5
    JournalFEBS Letters
    Issue number1-2
    Publication statusPublished - 16 Oct 1998


    • DNA ladder
    • Plant
    • Programmed cell death
    • Protoplast
    • Terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling
    • Ultraviolet-C light


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