TY - JOUR
T1 - Value of measuring serum procalcitonin, C-reactive protein, and mannan antigens to distinguish fungal from bacterial infections
AU - Petrikkos, G. L.
AU - Christofilopoulou, S. A.
AU - Tentolouris, N. K.
AU - Charvalos, E. A.
AU - Kosmidis, C. J.
AU - Daikos, G. L.
PY - 2005/4/1
Y1 - 2005/4/1
N2 - The study presented here was conducted to determine the diagnostic value of measuring procalcitonin, C-reactive protein, and mannan antigens to distinguish fungal from bacterial infections. The sensitivity and specificity of these measurements ranged from 35% to 97%. On days 1 and 3 following the onset of fever, both serum procalcitonin and C-reactive protein levels were lower in patients with fungal infections than in those with bacterial infections (p<0.0001). The presence of mannan antigens combined with a procalcitonin level <0.5 ng/ml provided higher specificity for distinguishing fungal from bacterial infections than each result alone.
AB - The study presented here was conducted to determine the diagnostic value of measuring procalcitonin, C-reactive protein, and mannan antigens to distinguish fungal from bacterial infections. The sensitivity and specificity of these measurements ranged from 35% to 97%. On days 1 and 3 following the onset of fever, both serum procalcitonin and C-reactive protein levels were lower in patients with fungal infections than in those with bacterial infections (p<0.0001). The presence of mannan antigens combined with a procalcitonin level <0.5 ng/ml provided higher specificity for distinguishing fungal from bacterial infections than each result alone.
UR - http://www.scopus.com/inward/record.url?scp=20044376122&partnerID=8YFLogxK
U2 - 10.1007/s10096-005-1312-z
DO - 10.1007/s10096-005-1312-z
M3 - Article
C2 - 15902534
AN - SCOPUS:20044376122
SN - 0934-9723
VL - 24
SP - 272
EP - 275
JO - European Journal of Clinical Microbiology and Infectious Diseases
JF - European Journal of Clinical Microbiology and Infectious Diseases
IS - 4
ER -