Viral respiratory tract infections and asthma: The course ahead

Louis A. Rosenthal, Pedro C. Avila, Peter W. Heymann, Richard J. Martin, E. Kathryn Miller, Nikolaos G. Papadopoulos, R. Stokes Peebles, James E. Gern

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Inquiries into the relationships between viral respiratory tract illnesses and the inception and exacerbation of asthma are being facilitated by recent advances in research approaches and technology. In this article we identify important knowledge gaps and future research questions, and we discuss how new investigational tools, including improved respiratory tract virus detection techniques, will permit current and future researchers to define these relationships and the host, virus, developmental, and environmental mechanisms that regulate them. A better understanding of these processes should facilitate the development of improved strategies for the prevention and treatment of virus-induced wheezing illnesses and asthma exacerbations and, possibly, the ultimate goal of discovering effective approaches for the primary prevention of asthma. © 2010 American Academy of Allergy, Asthma & Immunology.
    Original languageEnglish
    Pages (from-to)1212-1217
    Number of pages5
    JournalJournal of Allergy and Clinical Immunology
    Volume125
    Issue number6
    DOIs
    Publication statusPublished - Jun 2010

    Keywords

    • allergy
    • asthma
    • asthma exacerbations
    • asthma onset
    • respiratory syncytial virus
    • respiratory tract viruses
    • rhinovirus
    • Viral respiratory tract infections
    • wheezing

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