Viridans streptococcal bacteraemia in patients with haematological and solid malignancies

A D Burden; B A Oppenheim; D Crowther; A Howell; G R Morgenstern; J H Scarffe; N Thatcher

Viridans streptococcal bacteraemia in patients with haematological and solid malignancies

A D Burden, B A Oppenheim, D Crowther, A Howell, G R Morgenstern, J H Scarffe, N Thatcher

Division of Cancer Sciences (L5)

Research output: Contribution to journal › Article › peer-review

Abstract

Thirty-three episodes of septicaemia caused by viridans streptococci are reported in 32 adults under treatment for malignant diseases. The underlying diseases were acute leukaemia (17), lymphoma (4), myeloma (1), small cell carcinoma of the bronchus (6), carcinoma of the breast (2) and carcinoma of the stomach (2). Important predisposing factors included severe neutropenia and oral mucositis due to intensive chemotherapeutic regimens. There was a poor response to standard empirical antibiotics and a mortality of 12%. A role for prophylactic penicillin in high risk groups is suggested.

Original language	English
Pages (from-to)	409-411
Number of pages	3
Journal	European Journal of Cancer
Volume	27
Issue number	4
Publication status	Published - 1991

Keywords

Adolescent
Adult
Aged
Anti-Infective Agents
Female
Humans
Lymphoproliferative Disorders
Male
Middle Aged
Neoplasms
Sepsis
Streptococcal Infections
Journal Article

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Viridans streptococcal bacteraemia in patients with haematological and solid malignancies",

abstract = "Thirty-three episodes of septicaemia caused by viridans streptococci are reported in 32 adults under treatment for malignant diseases. The underlying diseases were acute leukaemia (17), lymphoma (4), myeloma (1), small cell carcinoma of the bronchus (6), carcinoma of the breast (2) and carcinoma of the stomach (2). Important predisposing factors included severe neutropenia and oral mucositis due to intensive chemotherapeutic regimens. There was a poor response to standard empirical antibiotics and a mortality of 12%. A role for prophylactic penicillin in high risk groups is suggested.",

keywords = "Adolescent, Adult, Aged, Anti-Infective Agents, Female, Humans, Lymphoproliferative Disorders, Male, Middle Aged, Neoplasms, Sepsis, Streptococcal Infections, Journal Article",

author = "Burden, {A D} and Oppenheim, {B A} and D Crowther and A Howell and Morgenstern, {G R} and Scarffe, {J H} and N Thatcher",

year = "1991",

language = "English",

volume = "27",

pages = "409--411",

journal = "European Journal of Cancer",

issn = "0959-8049",

publisher = "Elsevier BV",

number = "4",

}

TY - JOUR

T1 - Viridans streptococcal bacteraemia in patients with haematological and solid malignancies

AU - Burden, A D

AU - Oppenheim, B A

AU - Crowther, D

AU - Howell, A

AU - Morgenstern, G R

AU - Scarffe, J H

AU - Thatcher, N

PY - 1991

Y1 - 1991

N2 - Thirty-three episodes of septicaemia caused by viridans streptococci are reported in 32 adults under treatment for malignant diseases. The underlying diseases were acute leukaemia (17), lymphoma (4), myeloma (1), small cell carcinoma of the bronchus (6), carcinoma of the breast (2) and carcinoma of the stomach (2). Important predisposing factors included severe neutropenia and oral mucositis due to intensive chemotherapeutic regimens. There was a poor response to standard empirical antibiotics and a mortality of 12%. A role for prophylactic penicillin in high risk groups is suggested.

AB - Thirty-three episodes of septicaemia caused by viridans streptococci are reported in 32 adults under treatment for malignant diseases. The underlying diseases were acute leukaemia (17), lymphoma (4), myeloma (1), small cell carcinoma of the bronchus (6), carcinoma of the breast (2) and carcinoma of the stomach (2). Important predisposing factors included severe neutropenia and oral mucositis due to intensive chemotherapeutic regimens. There was a poor response to standard empirical antibiotics and a mortality of 12%. A role for prophylactic penicillin in high risk groups is suggested.

KW - Adolescent

KW - Adult

KW - Aged

KW - Anti-Infective Agents

KW - Female

KW - Humans

KW - Lymphoproliferative Disorders

KW - Male

KW - Middle Aged

KW - Neoplasms

KW - Sepsis

KW - Streptococcal Infections

KW - Journal Article

M3 - Article

C2 - 1828167

SN - 0959-8049

VL - 27

SP - 409

EP - 411

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 4

ER -

Viridans streptococcal bacteraemia in patients with haematological and solid malignancies

Abstract

Keywords

UN SDGs

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