Vitamin D and systemic lupus erythematosus - The hype and the hope

Yehuda Shoenfeld, Roberto Giacomelli, Shir Azrielant, Onorina Berardicurti, John A. Reynolds, Ian N. Bruce

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Over the past 20 years, much has been written about the potential role of vitamin D in on adverse health outcomes. In recent years, evidence has accumulated regarding the effect of vitamin D on the immune system, and its different cells. Some studies have noted lower vitamin D concentrations in patients with SLE. These epidemiological data still not answer the question: is vitamin D deficiency the cause or the effect? To answer this, we will discuss the association between vitamin D deficiency and SLE and review the evidence from interventional studies.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalAutoimmunity Reviews
Issue number1
Early online date3 Nov 2017
Publication statusPublished - Jan 2018


  • SLE
  • Systemic lupus erythematosus
  • Vitamin D
  • Vitamin D deficiency

Research Beacons, Institutes and Platforms

  • Manchester Institute for Collaborative Research on Ageing


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