Vitamin D and systemic lupus erythematosus - The hype and the hope

Yehuda Shoenfeld; Roberto Giacomelli; Shir Azrielant; Onorina Berardicurti; John A. Reynolds; Ian N. Bruce

doi:10.1016/j.autrev.2017.11.004

Vitamin D and systemic lupus erythematosus - The hype and the hope

Yehuda Shoenfeld^*, Roberto Giacomelli, Shir Azrielant, Onorina Berardicurti, John A. Reynolds, Ian N. Bruce

^*Corresponding author for this work

Division of Musculoskeletal & Dermatological Sciences (L5)

Research output: Contribution to journal › Review article › peer-review

81 Downloads (Pure)

Abstract

Over the past 20 years, much has been written about the potential role of vitamin D in on adverse health outcomes. In recent years, evidence has accumulated regarding the effect of vitamin D on the immune system, and its different cells. Some studies have noted lower vitamin D concentrations in patients with SLE. These epidemiological data still not answer the question: is vitamin D deficiency the cause or the effect? To answer this, we will discuss the association between vitamin D deficiency and SLE and review the evidence from interventional studies.

Original language	English
Pages (from-to)	19-23
Number of pages	5
Journal	Autoimmunity Reviews
Volume	17
Issue number	1
Early online date	3 Nov 2017
DOIs	https://doi.org/10.1016/j.autrev.2017.11.004
Publication status	Published - Jan 2018

Keywords

SLE
Systemic lupus erythematosus
Vitamin D
Vitamin D deficiency

Research Beacons, Institutes and Platforms

Manchester Institute for Collaborative Research on Ageing

Access to Document

10.1016/j.autrev.2017.11.004

VitDfinalversionacceptedAccepted author manuscript, 45 KBLicence: CC BY-NC-ND

Cite this

@article{ff5f2d7b4858476b8cd64799a4468dab,

title = "Vitamin D and systemic lupus erythematosus - The hype and the hope",

abstract = "Over the past 20 years, much has been written about the potential role of vitamin D in on adverse health outcomes. In recent years, evidence has accumulated regarding the effect of vitamin D on the immune system, and its different cells. Some studies have noted lower vitamin D concentrations in patients with SLE. These epidemiological data still not answer the question: is vitamin D deficiency the cause or the effect? To answer this, we will discuss the association between vitamin D deficiency and SLE and review the evidence from interventional studies.",

keywords = "SLE, Systemic lupus erythematosus, Vitamin D, Vitamin D deficiency",

author = "Yehuda Shoenfeld and Roberto Giacomelli and Shir Azrielant and Onorina Berardicurti and Reynolds, {John A.} and Bruce, {Ian N.}",

year = "2018",

month = jan,

doi = "10.1016/j.autrev.2017.11.004",

language = "English",

volume = "17",

pages = "19--23",

journal = "Autoimmunity Reviews",

issn = "1568-9972",

publisher = "Elsevier BV",

number = "1",

}

TY - JOUR

T1 - Vitamin D and systemic lupus erythematosus - The hype and the hope

AU - Shoenfeld, Yehuda

AU - Giacomelli, Roberto

AU - Azrielant, Shir

AU - Berardicurti, Onorina

AU - Reynolds, John A.

AU - Bruce, Ian N.

PY - 2018/1

Y1 - 2018/1

N2 - Over the past 20 years, much has been written about the potential role of vitamin D in on adverse health outcomes. In recent years, evidence has accumulated regarding the effect of vitamin D on the immune system, and its different cells. Some studies have noted lower vitamin D concentrations in patients with SLE. These epidemiological data still not answer the question: is vitamin D deficiency the cause or the effect? To answer this, we will discuss the association between vitamin D deficiency and SLE and review the evidence from interventional studies.

AB - Over the past 20 years, much has been written about the potential role of vitamin D in on adverse health outcomes. In recent years, evidence has accumulated regarding the effect of vitamin D on the immune system, and its different cells. Some studies have noted lower vitamin D concentrations in patients with SLE. These epidemiological data still not answer the question: is vitamin D deficiency the cause or the effect? To answer this, we will discuss the association between vitamin D deficiency and SLE and review the evidence from interventional studies.

KW - SLE

KW - Systemic lupus erythematosus

KW - Vitamin D

KW - Vitamin D deficiency

UR - http://www.scopus.com/inward/record.url?scp=85034643933&partnerID=8YFLogxK

U2 - 10.1016/j.autrev.2017.11.004

DO - 10.1016/j.autrev.2017.11.004

M3 - Review article

C2 - 29108830

AN - SCOPUS:85034643933

SN - 1568-9972

VL - 17

SP - 19

EP - 23

JO - Autoimmunity Reviews

JF - Autoimmunity Reviews

IS - 1

ER -

Vitamin D and systemic lupus erythematosus - The hype and the hope

Abstract

Keywords

Research Beacons, Institutes and Platforms

Access to Document

Other files and links

Fingerprint

Cite this