When day meets night: Subsiding calcium signalling translates daylight into new neurones

Alexei Verkhratsky, Govindan Dayanithi

Research output: Contribution to journalComment/debatepeer-review

Abstract

Day/night cycle controls neurogenesis; melatonin released from pineal gland in darkness stimulates intracellular Ca2+ dynamics thus decreasing proliferation of neural stem cells. In the daylight intracellular Ca2+ activity subsides, which stimulates neural stem cells division and increases generation of newborn neurones.

Original languageEnglish
Article number102385
JournalCell calcium
Volume95
DOIs
Publication statusPublished - May 2021

Keywords

  • Ca signalling
  • Day/Night cycle
  • Melatonin
  • Neural stem cells
  • Neurogenesis
  • Radial astrocytes

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