WSsas: A web service for the annotation of functional residues through structural homologues

David Talavera, Roman A. Laskowski, Janet M. Thornton

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Motivation: Annotation tools help scientists to traverse the gap between characterized and uncharacterized proteins. Tools for the prediction of protein function include those which predict the function of entire proteins or complexes, those annotating functional domains and those which predict specific residues within the domain. We have developed WSsas, a web service focused on the annotation of essential functional residues. WSsas uses similarity searches and pairwise alignments to transfer functional information about binding, catalytic and protein-protein interaction residues from solved structures to query sequences. In addition, WSsas can supply information about the relevant functional atoms. © The Author 2009. Published by Oxford University Press. All rights reserved.
    Original languageEnglish
    Pages (from-to)1192-1194
    Number of pages2
    JournalBioinformatics
    Volume25
    Issue number9
    DOIs
    Publication statusPublished - 2009

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