Zinc Sulfide Nanoparticle-decorated Fibre Mesh to Enable Localized H2S-amplified Chemotherapy

Gang Wang, Dong Cen, Zhaohui Ren, Yifan Wang, Xiujun Cai, Xiaohui Chen, Xiang Li, Serena M. Best, Gaorong Han

Research output: Contribution to journalArticlepeer-review

196 Downloads (Pure)

Abstract

For the first time, we report the design and fabrication of a ZnS nanoparticle-decorated silica fibre mesh (ZnS@SiO2) for localized H2S-amplified chemotherapy. With incorporation of DOX, implanted ZnS@SiO2 fibres enable sufficient on-site drug dosage and intracellular H2S content, inducing significant in vitro and in vivo tumour inhibition.
Original languageEnglish
Pages (from-to)4304-4307
Number of pages4
JournalChemical Communications
Volume56
Issue number31
DOIs
Publication statusPublished - 21 Apr 2020

Fingerprint

Dive into the research topics of 'Zinc Sulfide Nanoparticle-decorated Fibre Mesh to Enable Localized H2S-amplified Chemotherapy'. Together they form a unique fingerprint.

Cite this