ZrCl2(η-C5Me5)2-AlHCl 2·(THF)2: Efficient hydroalumination of terminal alkynes and cross-coupling of the derived alanes

Philip Andrews; Christopher M. Latham; Marc Magre; Darren Willcox; Simon Woodward

doi:10.1039/c2cc37537k

ZrCl2(η-C5Me5)2-AlHCl 2·(THF)2: Efficient hydroalumination of terminal alkynes and cross-coupling of the derived alanes

Philip Andrews, Christopher M. Latham, Marc Magre, Darren Willcox, Simon Woodward

Inorganic Chemistry Group

Research output: Contribution to journal › Article › peer-review

Abstract

Stabilized AlHCl2·(THF)2 hydroaluminates RCCH with exceptional chemo-, regio- and stereoselectivity under efficient ZrCl 2(η-C5Me5)2 catalysis (2-5 mol%). The resulting vinyl alanes undergo palladium cross-coupling with a wide range of sp2 electrophiles (aryl, heteroaryl and vinyl halides/pseudohalides) in good to excellent yields.

Original language	English
Pages (from-to)	1488-1490
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	15
DOIs	https://doi.org/10.1039/c2cc37537k
Publication status	Published - 21 Feb 2013

Keywords

Vinyl chloride
Alkynes
Palladium
Polyvinyl chloride

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10.1039/c2cc37537k

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title = "ZrCl2(η-C5Me5)2-AlHCl 2·(THF)2: Efficient hydroalumination of terminal alkynes and cross-coupling of the derived alanes",

abstract = "Stabilized AlHCl2·(THF)2 hydroaluminates RCCH with exceptional chemo-, regio- and stereoselectivity under efficient ZrCl 2(η-C5Me5)2 catalysis (2-5 mol%). The resulting vinyl alanes undergo palladium cross-coupling with a wide range of sp2 electrophiles (aryl, heteroaryl and vinyl halides/pseudohalides) in good to excellent yields. ",

keywords = "Vinyl chloride, Alkynes, Palladium, Polyvinyl chloride",

author = "Philip Andrews and Latham, {Christopher M.} and Marc Magre and Darren Willcox and Simon Woodward",

year = "2013",

month = feb,

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doi = "10.1039/c2cc37537k",

language = "English",

volume = "49",

pages = "1488--1490",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - ZrCl2(η-C5Me5)2-AlHCl 2·(THF)2: Efficient hydroalumination of terminal alkynes and cross-coupling of the derived alanes

AU - Andrews, Philip

AU - Latham, Christopher M.

AU - Magre, Marc

AU - Willcox, Darren

AU - Woodward, Simon

PY - 2013/2/21

Y1 - 2013/2/21

N2 - Stabilized AlHCl2·(THF)2 hydroaluminates RCCH with exceptional chemo-, regio- and stereoselectivity under efficient ZrCl 2(η-C5Me5)2 catalysis (2-5 mol%). The resulting vinyl alanes undergo palladium cross-coupling with a wide range of sp2 electrophiles (aryl, heteroaryl and vinyl halides/pseudohalides) in good to excellent yields.

AB - Stabilized AlHCl2·(THF)2 hydroaluminates RCCH with exceptional chemo-, regio- and stereoselectivity under efficient ZrCl 2(η-C5Me5)2 catalysis (2-5 mol%). The resulting vinyl alanes undergo palladium cross-coupling with a wide range of sp2 electrophiles (aryl, heteroaryl and vinyl halides/pseudohalides) in good to excellent yields.

KW - Vinyl chloride

KW - Alkynes

KW - Palladium

KW - Polyvinyl chloride

UR - http://www.mendeley.com/research/zrcl2%CE%B7c5me52alhcl-2thf2-efficient-hydroalumination-terminal-alkynes-crosscoupling-derived-alanes

U2 - 10.1039/c2cc37537k

DO - 10.1039/c2cc37537k

M3 - Article

VL - 49

SP - 1488

EP - 1490

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 15

ER -

ZrCl2(η-C5Me5)2-AlHCl 2·(THF)2: Efficient hydroalumination of terminal alkynes and cross-coupling of the derived alanes

Abstract

Keywords

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