Inflammatory Bowel Disease in Immigrant populations

Abstract

Background and Aims: The impact of ethnicity and migration on IBD phenotype and disease course and other outcomes is understudied. The aim of this work was to delineate the phenotype and disease course of Australian IBD patients of Middle Eastern descent and UK IBD patients of South Asian descent. IBD-related knowledge, information resource and Complementary and alternative medicine (CAM) use was also characterised in Middle Eastern patients. Methods: IBD phenotype and disease course was characterised through retrospective case-control studies. A prospective questionnaire-based cross-sectional survey was also undertaken to assess IBD-related knowledge and other outcomes in Middle Eastern patients. Results: In Australia, 250 Middle Eastern and 250 age-at-diagnosis (median 26.0 vs. 26.0 years; P=0.30) and disease duration (median 7.0 vs. 7.5 years; P=0.33) group-matched white Caucasians were compared. CD was more common than UC in Middle Eastern patients. Middle Eastern patients were more likely than white Caucasians to have a family history of IBD (31.5% vs. 15.6%; P

Date of Award	1 Aug 2017
Original language	English
Awarding Institution	The University of Manchester
Supervisor	John Mclaughlin (Supervisor), Simon Campbell (Supervisor) & Scott Levison (Supervisor)