Synthesis of Some Novel Chiral Dendrimers 1,1-Binaphthyl Derivatives

Abstract

Despite a number of reports on synthetic methods for 1,1'- binaphthyl molecules with a substitution in certain positions, to the best of our knowledge neither the synthesis of binaphthyl-based chiral dendrimers by 1,3-cycloaddition reactions, "Click" chemistry, or attempts to achieve the substitution in multiple potential positions on binaphthyl cores has been studied yet. Previously reported optically active binaphthyl-based dendrimers have shown application in a number of applications, such as in asymmetric catalysts, enantioselective fluorescent sensors and chiral molecular recognition. Therefore, this project will focus on the synthesis of some novel chiral multiply functionalized 1,1'-binaphthyl molecules, including those that contain suitable groups to enable "Click" reactions and to facilitate the synthesis of some symmetric and asymmetric chiral dendrimers.

Date of Award	1 Aug 2011
Original language	English
Awarding Institution	The University of Manchester
Supervisor	John Gardiner (Supervisor)